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轻度至中度性结肠炎患者的管理和治疗优化
Ferdinando D'Amico1,2, Ernesto Fasulo1, Vipul Jairath3
1Gastroenterology and Endoscopy, IRCCS Ospedale San Raffaele and Vita-Salute San Raffaele University, Milan, Italy.
轻度至中度性结肠炎 (UC) 的管理是具有挑战性的. 本综述探讨了定义,治疗和新技术,以个性化护理和改善患者的生活质量.
科学领域:
- 胃肠病学和炎症性肠病研究
- 慢性疾病的临床管理 慢性疾病的临床管理
背景情况:
- 性结肠炎 (UC) 构成了全球健康的重大负担.
- 由于分类异质和非标准化治疗方法,目前对轻度至中度UC的管理面临挑战.
研究的目的:
- 审查当前的证据和识别知识差距,以优化在轻度至中度UC临床决策.
- 探索定义,治疗目标和针对个性化患者护理的新兴技术.
主要方法:
- 在PubMed,Medline和Embase的综合文献搜索到2023年8月.
- 调查当前的医疗治疗方法,包括梅萨拉和皮质类固醇.
- 探索新兴技术,如肠道超声波,远程医疗和家庭测试.
主要成果:
- 疾病活动分层的不一致性阻碍了量身定制的治疗方案.
- 非侵入性技术和家庭测试可以增强个性化的UC管理模型.
- 个性化,以患者为中心的护理模式显示出改善生活质量的承诺.
结论:
- 标准化疾病活动分层对于使治疗与患者个人资料保持一致至关重要.
- 非侵入性诊断和个性化护理模式的进步是改善UC管理的关键.
- 共享决策和患者参与对于最大限度地提高性结肠炎的结果至关重要.
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