生物模拟性黑色素的双重性质
Alexandra Mavridi-Printezi1, Stefano Giordani1, Arianna Menichetti1,2
1Department of Chemistry "Giacomo Ciamician", Via Selmi 2, 40126 Bologna, Italy. valentina.marassi@unibo.it.
Nanoscale
|December 7, 2023
概括
类似黑色素的聚多巴胺合成产生了两个不同的纳米材料:密集的纳米粒子和低密度的聚合物. 这些多多巴胺 (PDA) 物种具有不同的特性和形成时间,影响了它们的应用.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
- 生物材料是一种生物材料.
背景情况:
- 黑色素启发的纳米材料利用独特的健康,环境和能源应用的特性.
- 目前的合成通常使用来自多巴胺等分子前体的自下而上的方法.
- 功能性黑色素构建块被纳入纳米结构和表面.
研究的目的:
- 研究多种纳米物种在多巴胺氧化聚合过程中同时形成的过程.
- 描述这些共同形成的多多巴胺 (PDA) 材料的不同组成,形态和特性.
- 了解PDA纳米粒子 (NP) 和聚合物的形成动力学和结构-性质关系.
主要方法:
- 多巴胺的氧化聚合合成类似黑色素的多巴胺 (PDA).
- 使用流场分化 (FFF) 分离和实时分析纳米物种.
- 使用TEM,UV-vis,光,光散射,DLS,FTIR,z电位,凝电泳和pH定位进行表征.
主要成果:
- 在PDA合成过程中,密集纳米粒子 (NP) 和低密度聚合物的同时形成.
- 通过自我组装,NP形成发生在前6小时内,而聚合物形成持续36小时.
- 该聚合物表现出更高的甲基醇含量和抗氧化活性;NP显示出更有效的Vis-NIR光衰减和光散射,但没有光.
结论:
- 多巴胺聚合会产生具有独特特性的异质PDA产品.
- 这些PDA物种的分离和表征对于有针对性的应用至关重要.
- 了解PDA NP和聚合物的差异性质为材料设计开辟了新的途径.
相关概念视频
Pigmentation
2.4K
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
2.4K
Epistasis
46.9K
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
46.9K
Epistasis Analysis
5.0K
Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
5.0K
Gene Duplication and Divergence
6.1K
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
6.1K
Position-effect Variegation
6.3K
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
6.3K
Photoreceptors and Visual Pathways
6.0K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.0K


