怀孕前的睡眠时间,非白天的工作时间表和自发流产的发生率:一个前性队列研究
J C Bond1, C M Coleman1, J J Yland1
1Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
Human reproduction (Oxford, England)
|December 7, 2023
概括
男人睡眠时间短和非白天工作时间安排在任何伴侣可能会增加自发流产 (SAB) 的风险. 女性的睡眠时间与SAB发病率几乎没有关联. 不一致的工作时间表,特别是男性的工作时间表,与较高的SAB率有关.
科学领域:
- 生殖流行病学 生殖流行病学
- 职业健康 职业健康 职业健康
- 睡眠科学 睡眠科学
背景情况:
- 之前的研究将睡眠时间短暂和某些职业暴露与不良生殖结果联系起来.
- 没有研究探讨了自发流产 (SAB) 风险,涉及男性睡眠/工作时间表或联合情侣暴露.
研究的目的:
- 调查双方合作伙伴自我报告的睡眠时间和非白天工作时间之间的联系以及自发流产 (SAB) 的发生率.
主要方法:
- 对9357名女性和2602名伴侣进行前性队列研究,通过问卷评估睡眠和工作时间表.
- 用于分析SAB风险的多变量Cox比例危险模型,对选择偏差进行反向概率加权.
主要成果:
- 女性睡眠时间短 (<6小时) 与SAB没有显著的关联. 男人睡眠时间短暂与SAB风险增加有轻微联系 (HR 1.30).
- 女性夜间工作 (HR 1.19) 和男性非白天工作 (HR 1.26) 与适度更高的SAB率有关.
- 男性伴侣在非白天班工作的不一致的工作时间表显示,与白天班工作的夫妇相比,SAB率较高 (HR1.46).
结论:
- 男性的睡眠时间和非白天的工作时间表,以及不一致的夫妇工作时间表,可能会影响自发流产 (SAB) 风险.
- 研究结果强调了男性职业因素和夫妇工作与生活融合对怀孕结果的潜在影响.
相关概念视频
Insufficient Sleep and Sleep Deprivation
147
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
147
Spermatogenesis
102.6K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.6K
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K


