前列腺素E2影响自然杀手细胞抗瘤免疫反应的多个阶段

Chloe Patterson1, Khodor S Hazime2, Santiago Zelenay1,3

  • 1The Lydia Becker Institute of Immunology and Inflammation, The University of Manchester, Manchester, United Kingdom.

PubMed
概括

前列腺素E2 (PGE2) 通过改变受体表达和迁移,损害自然杀手 (NK) 细胞的抗瘤功能. 这项研究揭示了PGE2如何抑制NK细胞的杀死,为癌症免疫治疗提供了洞察力.

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