卵巢囊对卵巢储备和生育能力的影响:一个病例对照研究

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Hasmik Bareghamyan^1,2, Armine Chopikyan³, Marine Petrosyan¹

¹Department of Obstetrics and Gynecology N1, Yerevan State Medical University, Yerevan, Armenia.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

|December 7, 2023

概括

卵巢囊和囊切除术显著影响青少年女性的卵巢储备标志物. 个性化支持对于维持这些患者的生育能力至关重要.

科学领域:

生殖内分泌学生殖内分泌学
妇科妇科医生妇科
儿科手术儿科手术

背景情况:

卵巢囊在青少年女性中很常见.
大型或复杂的囊通常需要进行手术 (囊切除术).
卵巢囊和囊切除术对青少年卵巢储量的影响仍然是积极研究的领域.

研究的目的:

评估卵巢囊和囊切除术对亚美尼亚青少年女性卵巢储备标志物的影响.
为了比较卵巢储备标记在有卵巢囊/切除囊后和健康对照的青少年之间.

主要方法:

预期病例控制研究设计.
包括三个组:经过单侧卵巢切除术 (POG) 术后,良性卵巢囊 (BOCG,直径≥5cm) 和参考组 (RFG,没有卵巢病理).
在基线和6个月后随访时测量抗穆勒尔激素 (AMH),卵泡刺激激素 (FSH) 和 antral卵泡计数 (AFC).

主要成果:

与RFG相比,6个月后在POG和BOCG中AMH和AFC水平显著下降.
与BOCG相比,在POG中观察到AMH和AFC的较大减少.
6个月后,BOCG中FSH水平没有显著变化.
与对照人群相比,患有子宫内膜瘤和囊瘤的参与者减少了AMH和AFC水平.

结论:

良性卵巢囊 (≥5cm) 和囊切除术在干预后6个月统计影响卵巢储备.
患有卵巢囊或经历了囊切除术的青少年需要量身定制的支持来保持生殖潜力.
早期监测和管理策略对于维持受影响青少年生育能力至关重要.

关键词:

青少年女性青少年女性复杂的卵巢囊卵巢囊卵巢囊切除术卵巢囊切除术卵巢储备 (OR) 是指卵巢的储备.

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