顺序性心内激活 节律失常的时间映射 没有信托时间参考
IEEE transactions on bio-medical engineering
|December 7, 2023
概括
一种用于局部激活时间 (LAT) 映射的新方法消除了对时间调整参考 (TAR) 的需求. 这种TARLess方法准确地绘制了心脏电活动,即使是复杂的波线,也可能减少手术时间和成本.
科学领域:
- 电子生理学 电子生理学
- 医疗成像医学成像
- 计算生物学 计算生物学
背景情况:
- 局部激活时间 (LAT) 映射对于理解心律失常至关重要.
- 目前的LAT映射技术通常依赖于稳定的时间对齐参考 (TAR) 来实现准确的相位对齐.
- 没有TAR可以使连续的电图记录变得复杂.
研究的目的:
- 开发和验证一种新的LAT映射方法,不需要时间对齐参考 (TARLess).
- 为了从无参考导管的连续记录中准确地绘制心脏激活映射.
主要方法:
- 开发了使用候选函数 (CF) 建模基于电极坐标的激活时间的TARLess方法.
- 顺序收集的电极坐标和LAT.
- 使用合成数据与模拟的波碰撞和来自心房的患者的临床数据验证了方法.
主要成果:
- 基于TARLess的映射方法产生了与传统基于TAR的方法可比的结果.
- 临床验证显示,TARLess和基于TAR的LAT测量之间的平均绝对差异为5.2 ±2.0毫秒.
- 该方法准确地绘制了心脏激活图,即使在复杂的场景中,如多个波面碰撞.
结论:
- 一种新的,无参考的LAT映射方法 (TARLess) 已经成功开发出来.
- 这种方法提供了准确的心脏激活图,没有时间对齐参考.
- TARLess映射提供了潜在的好处,包括减少手术持续时间,成本和并发症,因为它消除了对参考导管的需求.
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