伴随性疾病对非创伤性主要下肢截肢患者的死亡率的影响
Betül Keskinkılıç Yağız1, Ufuk Utku Göktuğ2, Ali Sapmaz3
1Ministry of Health Samsun Gazi State Hospital, Department of General Surgery, Samsun, Turkey.
Journal of wound care
|December 7, 2023
概括
大型下肢截肢导致高死亡率,超过50%的患者在三年内死亡. 晚年,糖尿病和功能衰竭显著增加截肢后的死亡风险.
科学领域:
- 血管外科 血管外科
- 老年医学 老年医学
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 较大的下肢截肢带有相当大的死亡风险.
- 非创伤性截肢通常与糖尿病和外周动脉疾病有关,需要仔细评估死亡率.
研究的目的:
- 为了调查30天,一年和三年的死亡率后的非创伤性较大的下肢截肢.
- 为了确定影响这些患者死亡风险的并发症.
主要方法:
- 对193名因糖尿病或外周动脉疾病而接受主要下肢截肢 (2010-2015年) 的患者的回顾性评估.
- 对人口统计数据,并发病,截肢水平,生存和死亡时间的分析.
- 使用卡普兰-梅尔分析,日志级别测试和考克斯回归来评估生存关联和风险因素.
主要成果:
- 总体而言,30天,一年和三年死亡率分别为16.6%,38.3%和60.1%.
- 年龄≥65岁是30天死亡率的重要预测因素 (HR:3.4).
- 年龄≥65岁 (HR:2.5),糖尿病 (HR:2) 和功能衰竭 (HR:2) 显著影响了三年死亡率.
结论:
- 在接受非创伤性主要下肢截肢的患者中,超过50%的患者在三年内死亡.
- 晚年,糖尿病和功能衰竭是增加死亡率的关键风险因素.
- 建议在截肢前强调保守的伤口护理,并进行进一步的前性研究.
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