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Updated: Jul 9, 2025

A Blood-based Test for the Detection of ROS1 and RET Fusion Transcripts from Circulating Ribonucleic Acid Using Digital Polymerase Chain Reaction
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导致ROSAH综合征或螺旋腺瘤的ALPK1突变被人类核酸糖激活

Tom Snelling1, Anton Saalfrank1, Nicola T Wood1

  • 1Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, United Kingdom.

Proceedings of the National Academy of Sciences of the United States of America
|December 7, 2023
PubMed
概括

非典型蛋白激酶1 (ALPK1) 的突变通过失去细菌ADP-肝素的特异性导致人类疾病,从而导致人类核酸糖的激活. 这会影响天生的免疫力和疾病的发展.

关键词:
在 ALPK1 中,罗莎 (ROSAH) 是一个名字.这就是TIFA TIFA.核酸糖是一种核酸糖.螺旋腺瘤是一种状腺瘤.

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