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Updated: Jul 9, 2025

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乳腺瘤相关和正常相邻的内皮细胞的 in situ 转录组景观

Akhilandeshwari Ravichandran1, James Monkman2, Ahmed M Mehdi3

  • 1School of Mechanical, Medical and Process Engineering, Faculty of Engineering, Queensland University of Technology, Kelvin Grove, QLD 4059, Australia; Centre for Biomedical Technologies, Queensland University of Technology (QUT), Brisbane, QLD 4059, Australia.

Biochimica et biophysica acta. Molecular basis of disease
|December 7, 2023
PubMed
概括

研究人员分析了三阴性乳腺癌 (TNBC) 内皮细胞与正常细胞的基因表达. 这揭示了不同的分子概况,为TNBC治疗中的抗血管性疗法提供了新的点.

关键词:
不正常的血管系统.空间配置文件的形成三重阴性乳腺癌是什么?瘤内皮细胞是瘤内皮细胞.分析整个转录组的分析.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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