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Updated: Jul 9, 2025

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对TAD的进化和功能表征揭示了哺乳动物TAD边界属性和功能中的多样性

Mariam Okhovat1, Jake VanCampen2, Kimberly A Nevonen2

  • 1Department of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA. okhovat@ohsu.edu.

Nature communications
|December 7, 2023
PubMed
概括

拓关联域 (TADs) 进化,超保守的边界显示出强大的基因调节. 特定物种的TAD边界变化影响基因表达和发育,突出了TAD进化.

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