相关实验视频

Updated: Jul 9, 2025

Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice
11:18

Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice

Published on: April 2, 2013

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血小板激活因子和蛋白酶激活受体2合作,通过核因子-kappa B的交换激活促进中性粒细胞的招募和肺炎

Irismara Sousa Silva1, Aline D Almeida1, Antônio C M Lima Filho2

  • 1Laboratory of Inflammation and Proteases, Department of Pharmacology, Institute of Biological Sciences (ICB), Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.

Scientific reports
|December 7, 2023
PubMed
概括

这项研究揭示了血小板激活受体 (PAFR) 和蛋白酶激活受体2 (PAR2) 在驱动肺炎和中性粒细胞招募方面的关键合作. 阻断PAR2显著降低了肺部的炎症反应.

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