慢性胃炎可能预测大脑小血管疾病的风险
Cunsheng Wei1, Chang Tan1, Xuemei Zhang1
1Department of Neurology, Affiliated Jiangning Hospital With Nanjing Medical University, 168 Gushan Road, Nanjing, 211100, Jiangsu, China.
慢性缩性胃炎增加了脑小血管疾病 (CSVD) 的风险. 建议在患有慢性缩性胃炎的患者进行CSVD常规查.
科学领域:
- 神经学 神经学
- 胃肠病学 胃肠病学
- 血管医学 血管医学
背景情况:
- 杆菌 (HP) 感染引起的慢性胃炎与缺血性中风风险有关.
- 慢性胃炎和大脑小血管疾病 (CSVD) 之间的关联尚未得到充分证实.
研究的目的:
- 研究慢性胃炎作为CSVD的潜在预测因素.
- 探索慢性胃炎及其相关条件作为CSVD的替代预测因素.
主要方法:
- 纳入了1191名年龄在18岁以上,接受电子胃镜检查的患者.
- 脑小血管疾病 (CSVD) 的存在和严重程度使用脑MRI进行评估,并建立了评分标准.
- 后勤回归分析确定了CSVD的潜在风险因素.
主要成果:
- 757名 (63.6%) 患者患有心血管疾病,而434名 (36.4%) 患者没有.
- 慢性缩性胃炎与CSVD风险增加显著相关 (调整后OR=1.58,P<0.05).
结论:
- 慢性缩性胃炎是与CSVD存在相关的重要危险因素.
- 在被诊断患有慢性缩性胃炎的患者中,有必要进行CSVD的例行查.
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