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Updated: Jul 9, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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结合突变异质性来识别富含癌症同义突变的基因

Yiyun Rao1, Nabeel Ahmed1,2, Justin Pritchard3

  • 1Huck Institute of the Life Sciences, Pennsylvania State University, University Park, State College, PA, 16802, USA.

BMC bioinformatics
|December 7, 2023
PubMed
概括

同名突变,不改变蛋白质序列,可以影响癌症的发展. 这项研究引入了MutSigCVsyn,以识别30个癌症相关基因,其中包括BCL-2等同突变,为癌症研究提供了新的途径.

关键词:
癌症驱动器 癌症驱动器变种 标志 标志CVV同名的突变是同名的突变.

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