人类暴露于柴油废气会诱导CYP1A1表达和AhR激活,而没有协调的抗氧化反应

M Friberg1, A F Behndig1, J A Bosson1

  • 1Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

PubMed
概括

在人类中,柴油废气 (DE) 暴露会激活基碳化合物受体 (AhR) 和CYP1A1,但不会激活Nrf2介导的抗氧化防御. 这表明DE会引起炎症并改变排毒,而无需立即保护细胞.

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