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Updated: Jun 7, 2026

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
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PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins

Published on: July 2, 2010

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GCLiPP:全球交联和蛋白质净化方法,用于构建RNA结合蛋白的高分辨率占用地图

Wandi S Zhu1, Adam J Litterman1, Harshaan S Sekhon1,2

  • 1Department of Microbiology & Immunology and Sandler Asthma Basic Research Center, University of California San Francisco, San Francisco, CA, USA.

Genome biology
|December 8, 2023
PubMed
概括

全球RNA互动原子捕获 (GCLiPP) 以高分辨率绘制了RNA结合蛋白 (RBP) 的占用情况. 该方法识别了人类和小鼠T细胞中保存的调节元件和与免疫相关的cis调节区域.

关键词:
关联监管要素 关联监管要素转录后的监管 转录后的监管它们是RNA结合蛋白 (RNA-binding proteins,简称RBP).在T细胞,T细胞.

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相关概念视频

Immunoprecipitation01:20

Immunoprecipitation

Immunoprecipitation, or IP, is a widely used technique that employs protein-antibody interactions to isolate proteins or protein complexes in their native state for studying protein-protein interactions, quaternary structures, or supramolecular complexes. Various modifications of the technique, including chromatin IP, cross-linking IP, and fluorescence IP, are commonly used.
Chromatin Immunoprecipitation
Chromatin immunoprecipitation, also known as ChIP, is used to study protein-DNA or...