怀孕前心律不整与妊娠期糖尿病之间的关联:韩国一项全国性基于人口的研究
You-Jung Choi1, Won Yung Wi2, Geum Joon Cho2
1Cardiovascular Center, Korea University Guro Hospital, Seoul, Korea.
Epidemiology and health
|December 8, 2023
概括
怀孕前的心律不整会增加妊娠期糖尿病 (GDM) 的风险. 患有心律不整的女性患有GDM的几率高出1.78倍,突出显著的关联.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 产科 产科 产科 产科 产科
背景情况:
- 心律不整在糖尿病患者中更为常见.
- 心律不整和妊娠糖尿病 (GDM) 之间的联系需要进一步调查.
研究的目的:
- 调查心律不整和GDM发病率之间的关联.
- 为了确定先前存在的心律不整是否会增加GDM风险.
主要方法:
- 使用韩国医疗保险服务数据 (2007-2015) 进行的回顾性队列研究.
- 分析了365,880个没有糖尿病病史的单独怀孕.
- 在0.9%的受试者中发现心律不整;在8.7%的受试者中诊断出GDM.
主要成果:
- 患有心律不整的女性患GDM的患病率更高 (14.9%对比8.7%,p<0.001).
- 在多变量分析中,心律不整仍然是GDM的重要危险因素 (aOR,1.78;95% CI,1.615-1.970).
- 根据年龄,BMI和高血压状况,这种联系在各个子组中是一致的.
结论:
- 预先存在的心律不整与患上GDM的风险增加有显著的关联.
- 这一发现强调了怀孕妇女心脏健康评估的重要性.
- 进一步的研究可能会探索连接心律失常和GDM的潜在机制.
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