脚神经肌肉功能障碍与收缩带综合征相关
Ana G Starcevich1, Leah R F Demetri2, Michelle A James3
1University of California Davis School of Medicine.
Journal of pediatric orthopedics
|December 8, 2023
概括
与收缩带综合征相关的脚神经肌肉缺陷可能不是由于带带直接损害神经. 这些脚通常需要更多的干预和长期支架.
科学领域:
- 整形外科 整形外科 整形外科
- 儿科手术 儿科手术
- 神经肌肉疾病 神经肌肉疾病
背景情况:
- 收缩带综合征 (CBS) 是一种先天性异常,通常与脚有关.
- 神经功能障碍可能发生在CBS脚中,但其原因尚不清楚.
研究的目的:
- 分析CBS球脚中的收缩带分布.
- 为了研究神经肌肉缺陷 (NMD) 和近位带之间的关联.
- 为了比较使用和不使用NMD的 clubfeet的治疗和结果.
主要方法:
- 对CBS脚患者 (1998-2018) 的回顾性审查.
- 纳入标准:Ponseti方法治疗,≥1年随访,详细的神经肌肉和带评估.
- 定义NMD是缺席脚背部屈曲.
主要成果:
- 在20名儿童中分析了26个脚; 46%的儿童患有NMD.
- NMD clubfeet没有与ipsilateral近接带 (42%对43%),没有显著的关联.
- 在NMD clubfeet中,白天使用脚和脚 (AFO) 的比率更高 (58%对14%).
结论:
- 在CBS clubfeet中的NMD可以在没有可见的近距离带的情况下发生,这表明了其他病因.
- 虽然在统计学上不显著,但NMD clubfeet显示了更多的造,复发和手术的趋势.
- 在NMD clubfeet中,长期白天使用AFO是常见的.
相关概念视频
Muscles of the Leg that Move the Foot and Toes
1.5K
The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
1.5K
Disorders of the Skeletal Muscle
962
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
962
Neuromuscular Junction And Blockade
3.1K
The site of chemical communication between a motor neuron and a muscle fiber is called the neuromuscular junction (NMJ). The end of the motor neuron at the NMJ divides into a cluster of synaptic end bulbs. The cytoplasm of these bulbs consists of synaptic vesicles enclosing acetylcholine molecules, the principal neurotransmitter released at the NMJ. The region opposite the synaptic bulb that ends in the muscle fiber is called the motor end plate, which has acetylcholine receptors. Within the...
3.1K
Actin Treadmilling
8.1K
Actin filaments undergo polymerization and depolymerization from either end. The polymerization and depolymerization rates depend on the cytosolic concentration of free G-actins. The polymerization rate is generally higher at the plus or barbed end, while the depolymerization rate is higher at the minus or pointed end. At a steady state, critical concentration describes the concentration of free G-actin monomers at which the polymerization rate at the plus end is equal to that of the...
8.1K


