在内镜切除后,对发烧和炎症反应增加的原因进行前性跨器官分析

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358

Mari Mizutani¹, Daisuke Minesaki², Kohei Morioka¹

¹Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University, School of Medicine, Tokyo, Japan.

Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

|December 8, 2023

概括

在内镜切除 (ER) 后发烧通常是由胃肠道上部的吸入性肺炎和结肠中的后ER凝结综合征引起的. 食道病变和大量灌增加了吸入性肺炎的风险.

科学领域:

胃肠病学胃肠病学
内視鏡外科手術內視鏡外科手術
肺部病理学肺部病理学

背景情况:

在内镜切除 (ER) 后的发烧和炎症因器官而异.
了解这些差异对于完善ER技术至关重要.
这项研究调查了ER后发烧和炎症的器官特异性原因.

研究的目的:

为了确定发烧和ER后C反应蛋白 (CRP) 升高的主要原因,在不同的胃肠道器官.
确定与ER后吸入性肺炎相关的风险因素.

主要方法:

对822名接受胃肠内镜下粘膜切割 (ESD) 或内镜粘膜切除 (EMR) 的患者进行前性研究.
主要终点:发烧和ER后CRP水平增加.
二次终点:吸入性肺炎的危险因素;诊断工具包括血液检查,X光学和CT扫描.

主要成果:

吸气性肺炎是食道 (53%),胃 (48%) 和十二指肠 (71%) 中ER后发烧的最常见原因.
在结直肠ESD (38%) 之后,后ER凝血综合征最常见.
吸入性肺炎的独立风险因素包括食道病变 (OR 3.57) 和≥1L灌液 (OR 3.71).

结论:

吸气性肺炎是上部胃肠道后发烧的主要原因.
在结直肠ESD后,后ER凝血综合征是普遍存在的.
食道损伤位置和高灌量是吸入性肺炎的关键风险因素.

关键词:

在C-反应性蛋白中,C-反应性蛋白是最重要的.吸入性肺炎是一种肺炎.进行内镜粘膜切除.进行内镜下膜剖析.这是一个前性研究.

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