加强支持性护理与患有恶性瘤的胃癌患者的生存率提高有关
John D Karalis1, Michelle R Ju1, Rachel Feig1
1Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Journal of surgical oncology
|December 8, 2023
概括
积极的支持性护理,包括营养和住院化疗,显著改善了胃癌患者的整体存活率 (OS). 这种方法为预后不佳的患者提供了希望.
科学领域:
- 在瘤学瘤学.
- 胃肠病学 胃肠病学
- 支持性护理是一种支持性护理.
背景情况:
- 患有恶性炎的胃癌由于功能状况和营养不良,预后不佳.
- 标准护理往往阻止这些患者的全身疗法.
- 一个多学科团队从2019年开始实施了一项积极的支持性护理计划.
研究的目的:
- 为了比较胃癌患者在实施积极的支持性护理计划之前和之后同步恶性炎的结果.
- 评估加强支持措施对整体存活率的影响.
主要方法:
- 胃腺癌患者与同步恶性炎 (2010-2022) 的回顾性审查.
- 历史控制时代 (2010-2018) 与积极支持性护理时代 (2019-2022) 的比较.
- 分析包括人口统计,临床特征和生存数据.
主要成果:
- 积极的支持性护理队列 (23名患者) 与历史对照 (31名患者) 相比,增加了补充营养 (30%vs3%) 和住院化疗 (39%vs3%) 的使用率.
- 化疗周期的中位数从5增加到9.5.5.
- 平均整体存活时间从5.4个月提高到10.4个月 (p=0.04).
结论:
- 积极的支持性护理措施,包括补充营养和住院化疗,改善了患有恶性瘤的胃癌患者的整体存活率.
- 这些发现表明,积极主动,积极的支持性护理可以在这个具有挑战性的患者群体中延长存活时间.
- 对于高风险患者,建议考虑住院化疗和营养支持.
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