在囊性纤维化中进行鼻多重症手术
Paula Ribeiro Lopes Almeida1,2, Osmar C Person1, Maria Es Puga3
1Collaborator of the Department of Otorhinolaryngology at Mario Covas State Hospital, School of Medicine ABC, Santo André - São Paulo, Brazil.
我们不确定内镜鼻腔外科手术是否能改善患有慢性鼻炎和鼻多重症的囊性纤维化患者的鼻症状或肺功能. 由于单一研究的证据确定性非常低,需要进行更多的研究.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 肺部病理学 肺部病理学
- 遗传学 遗传学 是一个
背景情况:
- 囊性纤维化 (Cystic fibrosis,CF) 是一种自体逆性疾病,导致异常的电解质分泌.
- 鼻鼻腔的分泌静止导致CF患者慢性鼻炎 (CRS) 和鼻多重症.
- 内镜鼻手术旨在改善鼻排水,并促进医疗治疗.
结论:
- 非常低的确定性证据妨碍了关于内镜鼻外科手术对CF中CRS与鼻多重症的疗效的最终结论.
- 建议未来的多中心研究采用更大的样本大小,客观结果和更长的随访.
- 在未来的研究中,考虑囊性纤维化跨膜导电性调节器 (CFTR调节器) 是很重要的.
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