,和电解质的稳定性在三个不同的管在患有基本血栓细胞瘤的患者

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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization

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Murat Aksit¹, Merve Zeytinli Aksit², Ayfer Colak¹

¹Medical Biochemistry Department, University of Health Sciences, Tepecik Training and Research Hospital, Izmir, Turkey.

Scandinavian journal of clinical and laboratory investigation

|December 8, 2023

概括

血液采集管的选择会影响基本血栓细胞瘤患者的,和水平. 与SST和LiH管相比,屏障管为这些电解质提供了更好的短期稳定性.

科学领域:

临床化学临床化学
血液学血液学血液学
实验室医学实验室医学

背景情况:

准确的血液采集和及时分析对于可靠的诊断结果至关重要.
不同的采血管可以影响电解质度,可能影响患者的诊断和管理.
基本血栓细胞瘤 (ET) 是一种由血小板数升高的髓增殖性瘤.

研究的目的:

为了比较 (K), (Ca) 和 (P) 度在血清分离管 (SST),没有凝的肝素管 (LiH) 和带有屏障的肝素管 (Barricor) 在患有基本血栓塞瘤 (ET) 的患者中.
为了评估这些电解质在试管类型中在室温下的短期稳定性.

主要方法:

40名ET患者的血液样本被收集到SST,LiH和Barricor管中.
采集后0,2,4小时和8小时测量K,Ca和P度.
管间比较采用了通过巴布洛克回归和布兰德-阿尔特曼分析,结果与生物变异数据库的最大允许差异 (MPD) 相比进行了评估.

主要成果:

在将SST与LiH管进行比较时,在所有分析品中观察到超过MPD的显著差异.
与LiH管相比,Barricor管中的和水平显示出超过MPD的差异,而则没有.
肝素管 (LiH) 在8小时内显示出所有三种电解质的临床显著变化; Barricor管保持了K,Ca和P的稳定性,长达8小时,Ca水平处于边界.

结论:

在使用SST管与LiH管相比,K,Ca和P度发生临床显著的改变.
与LiH管相比,屏障管显示K和Ca的显著变化较少,表明稳定性得到改善.
虽然所有类型的管都表现出长达4小时的稳定性,但LiH管在8小时后表现出显著的电解质变化,这凸显了及时分析和适当的管道选择的重要性.

关键词:

电解质是一种电解质.过高血症的情况.血清过高的高卡利米亚.过高酸盐血症的发生.血小板细胞形成的原因是血小板细胞分裂.

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