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Updated: Jul 31, 2026

Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
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Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3

Published on: December 27, 2010

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快速HIV-1基因型测定试验用于检测状突变

Nicolas Margot1, Vidula Naik1, Anurag Nekkalapudi1

  • 1Gilead Sciences Inc., Clinical Virology, Foster City, California, USA.

Journal of medical virology
|December 8, 2023
PubMed
概括

一种新方法从临床样本中快速测序人类免疫缺陷病毒 (HIV) 囊片段. 这有助于了解对新型HIV-1囊抑制剂 (如莱纳卡巴维尔) 的耐药性,这对于治疗失败分析至关重要.

关键词:
艾滋病病毒-1 艾滋病病毒-1卡普西德 (Capsid) 是一种体.这就是 lenacapavir.电阻的阻力可以

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An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

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相关概念视频

Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material for adaptive...