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Updated: Jul 9, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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细胞内K+限制T细胞耗尽,并保持抗瘤功能

Camille Collier1,2, Kelly Wucherer1,2, Matthew McWhorter1,2

  • 1Division of Surgical Oncology, Department of Surgery, Oregon Health & Science University, Portland, Oregon.

Cancer immunology research
|December 8, 2023
PubMed
概括

改变CD8+T细胞中的细胞内水平会影响其功能和疲劳. 通过基因编辑降低,虽然最初会导致功能障碍,但可以通过K+或抗氧化剂来控制,以恢复抗癌活性.

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