BRD4,RUNX2

Rachel E Musa1, Kaitlyn L Lester1, Gabrielle Quickstad1

  • 1Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, USA.

Development (Cambridge, England)
|December 8, 2023
PubMed
概括

康尼莉亚·德朗格综合征 (CdLS) 是由BRD4突变引起的,BRD4是一种对面发育至关重要的蛋白质. 神经细胞中的BRD4损失会损害骨质母细胞的分化,导致严重的面部异常.

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