心脏代谢指数与慢性病之间的关联:一个横截面研究
Qian Guo1, Yani Wang1, Yuchen Liu1
1Department of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, China.
International urology and nephrology
|December 8, 2023
概括
较高的心脏代谢指数 (CMI),是中心肥胖的一个指标,与美国普通人口中慢性病 (CKD) 风险增加有关. 这项研究发现,CMI水平升高与患CKD的可能性增加之间存在显著的关联.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 中枢肥胖是慢性病 (CKD) 的已知危险因素.
- 心脏代谢指数 (CMI) 和慢性病发病率之间的特定关系需要进一步研究.
- 了解这种关联对于针对代谢综合征和脏健康的公共卫生策略至关重要.
研究的目的:
- 调查心脏代谢指数 (CMI) 与慢性病 (CKD) 风险之间的相关性.
- 在美国普通人口的大型代表性样本中评估该协会.
- 为了确定更高的CMI水平是否独立地与增加的CKD风险有关.
主要方法:
- 一项横截面研究利用了来自国家健康和营养检查调查 (NHANES) (1999-2020) 的20岁及以上的64,313名参与者的数据.
- 参与者根据CMI第三方 (T1,T2,T3) 进行了分类,分为三组.
- 使用NHANES推的权重进行后勤回归分析,以评估CMI和CKD之间的关联.
主要成果:
- 在包括的21,765名参与者中,CKD的总体患病率为12.2%.
- 随着CMI的上升,CKD的患病率显著增加,从T1的8.9%增加到T3的16.0% (P<0.001).
- 经过对混因素进行调整后,较高CMI的三位体表现出显著更高的CKD风险 (T3与T1:OR1.22,95%CI1.05-1.43,P=0.013).
结论:
- 心脏代谢指数 (CMI) 的升高与慢性病 (CKD) 的风险增加独立相关.
- 这些发现凸显了监测CMI的重要性,作为对一般人群中CKD风险的潜在指标.
- 公共卫生倡议可能受益于将CMI评估纳入预防和管理病的战略.
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