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一个ex-vivo和in-vitro动态模拟器用于外科手术和透导管中枢干预

Roger Karl^1,2,3,4, Gabriele Romano^5,6, Josephin Marx^5,7,6

¹Ruprecht-Karls University of Heidelberg, Heidelberg, Germany. roger.karl@med.uni-heidelberg.de.

International journal of computer assisted radiology and surgery

|December 8, 2023

概括

一个新的模拟器准确地模拟了中膜 (MV) 病理和修复程序,如微创MV手术 (MIMVS) 和跨导管端到端修复 (TEER). 这个工具可以实现复杂的MV治疗的现实训练和个性化规划.

科学领域:

心血管外科心血管外科
生物医学工程生物医学工程
医疗模拟医疗模拟

背景情况:

微创性 mitra 门手术 (MIMVS) 和跨导管端到端修复 (TEER) 对于治疗 mitra 门 (MV) 病理至关重要.
对于这些复杂的程序,培训机会有限.
现实的血液动力学环境对于有效的培训和程序规划至关重要.

研究的目的:

开发和验证一种用于调查MV病理的新型模拟器.
为了在血液动力学环境中实现MIMVS和TEER程序的真实模拟.
为培训和个性化规划MV干预提供一个平台.

主要方法:

模拟器配备了各种 mitra 门,包括假体,有能力的猪和病理改变的猪门 (chordae tendineae 破裂,扩张的环).
还使用了一种患者特异的MV,具有双叶子性脱落.
记录了压力,流量和横食道心声测量,并在模拟器上进行了专家执行的MIMVS和TEER程序.

主要成果:

模拟器准确地复制了生理条件,合格的MV测量在正常范围内.
病理性MVs显示吐量增加 (RVol).
无论是MIMVS还是TEER程序都成功地减少了RVols,减轻了额头吐的严重程度.

结论:

活体模拟器实际模拟了 MV 病理和修复的 in-vivo 条件.
模拟器促进了MIMVS和TEER的性能,包括患者特定的病例.
这项技术为培训模式和个性化治疗规划提供了新的临床前景.

关键词:

动态物理模拟器动态物理模拟器最少侵入性的 mitra 门手术.中心门维修 - - 中心门维修针对患者的具体规划跨导管边缘到边缘维修

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