基于协议的连续和间歇性输管养在机械通风的重症儿童的比较 - 一个开放的标签随机对照试验
Vijaya Kumar1, Jhuma Sankar1, Manisha Jana2
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, 110029, India.
Indian journal of pediatrics
|December 8, 2023
概括
连续输管养 (CTF) 和间歇输管养 (ITF) 在重症儿童达到目标卡路里和蛋白质的时间上没有显著差异. 这两种肠道营养方法在营养支持方面同样有效.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
背景情况:
- 优化营养供应对于重症儿童至关重要.
- 肠道营养是首选的,但输送方法各不相同.
- 连续管养 (CTF) 和间歇管养 (ITF) 是常见的方法.
研究的目的:
- 为了比较CTF与ITF在重症儿童中的疗效.
- 为了确定达到目标卡路里和蛋白质摄入量的时间.
- 评估二次结果,包括料不耐受性和死亡率.
主要方法:
- 在儿科重症监护室 (PICU) 进行随机试验.
- 儿童被随机分配到CTF或ITF组.
- 主要结局:达到70%的世界卫生组织目标卡路里和1.5g/kg的目标蛋白质的时间.
主要成果:
- 在CTF和ITF之间达到目标卡路里 (p=0.69) 或蛋白质 (p=0.55) 的时间没有显著差异.
- 目标卡路里的中位时间:1.7天 (CTF) 与1.8天 (ITF).
- 其他结果,包括死亡率和料不耐受性,没有显著差异.
结论:
- 在重症儿童中,CTF和ITF在实现营养目标方面表现出相似的有效性.
- 养方法的选择可能不会影响营养递送的速度.
- 进一步的研究可以探索以患者为中心的结果.
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