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尼古丁胺胺单核酸通过抑制喘中的SIRT3 SUMOylation来减轻呼吸道上皮质屏障功能障碍

Jiayuan Liang1, Chi Zhou1, Changyun Zhang1

  • 1Department of Respiratory and Critical Care Medicine, Chronic Airways Diseases Laboratory, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

International immunopharmacology
|December 8, 2023
PubMed
概括

尼古丁胺胺单核酸 (NMN) 可以通过改善呼吸道炎症和屏障功能来治疗过敏喘. 这通过抑制SIRT3 SUMOylation而发生,提供了潜在的新疗法策略.

关键词:
喘 喘 是一种皮质屏障功能障碍 皮质屏障功能障碍尼古丁胺胺单核酸是什么在SIRT3中,SIRT3是最重要的.这就是SUMOylation的作用.

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