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Updated: Jul 9, 2025

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
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结肠干细胞两极分化的致癌现象

Xiao Qin1, Ferran Cardoso Rodriguez1, Jahangir Sufi1

  • 1Cell Communication Lab, Department of Oncology, University College London Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK.

Cell
|December 8, 2023
PubMed
概括

结肠直肠癌 (CRC) 突变会覆盖正常的细胞通信,将细胞陷入超增殖状态. 这项研究揭示了瘤基因和微环境信号如何相互作用来控制结肠癌中的细胞命运.

关键词:
美国细胞可塑性细胞对细胞的信号传输细胞命运两极分化结肠干细胞大肠直肠癌提示信号响应有机物单细胞分析瘤微环境

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