癌症诊断后戒烟干预措施的有效性:系统性审查和元分析
Peter R Scholten1, Lukas J A Stalpers2, Iris Bronsema1
1Center for Gynaecologic Oncology Amsterdam, Amsterdam UMC, University of Amsterdam, location AMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands; Department of Radiotherapy, Amsterdam UMC, University of Amsterdam, location AMC, Meibergdreef 9, 1105 AZ Amsterdam, the Netherlands.
联合干预措施对癌症患者戒烟最有效. 这包括药理和行为支持,导致更好的结果和生存率.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 行为科学 行为科学
背景情况:
- 吸烟会对癌症治疗结果产生负面影响,增加副作用并降低生存率.
- 对癌症患者的戒烟支持至关重要,应纳入标准护理.
- 确定有效的戒烟策略对于改善患者预后至关重要.
研究的目的:
- 系统地审查和确定癌症诊断的个人戒烟最有效的方法.
- 评估各种干预措施在帮助癌症患者戒烟方面的有效性.
主要方法:
- 在PubMed,Embase,Web of Science和谷歌学者中进行了系统的文献搜索.
- 包括的研究是2000年1月之后发表的随机对照试验和观察性研究,重点关注癌症患者的戒烟干预措施.
- 结果使用元分析进行评估,研究质量根据GRADE标准进行评估.
主要成果:
- 对18项RCT和3项观察性研究的元分析表明,联合药理和行为干预措施 (OR 1.67) 和单独行为干预措施 (OR 1.33) 有显著的益处.
- 单一模式的药理干预没有显示出癌症患者戒烟的统计学上显著的益处 (OR 1.11).
- 包括的研究的整体方法质量被评为非常低.
结论:
- 药理和行为干预的结合似乎是癌症患者戒烟的最有效方法.
- 建议将全面的戒烟支持纳入癌症护理,以改善患者的治疗结果.
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