两个冷却气球之间的组织温度变化的差异
Takahiro Hayashi1,2, Kohei Hamada3, Kiyotaka Iwasaki4,3,5
1Cooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women's Medical University and Waseda University, Shinjuku-ku, Japan th.tohoku.univ@gmail.com.
Open heart
|December 8, 2023
概括
波拉克斯冷却气球系统的冷生物组织明显比北极前线先进的Pro (AFA-Pro) 系统更冷. 组织温度的这种差异可能解释了在心房移除过程中Polarx观察到的更高的并发症率.
科学领域:
- 心血管干预 心血管干预
- 电子生理学 电子生理学
- 医疗器械技术 医疗器械技术
背景情况:
- 北极前部提前Pro (AFA-Pro) 是一个标准的冷气球用于心房动 (AF) 消退.
- 新的POLARx冷热气球系统显示了类似的急性结果,但并发症率更高,包括神经.
- 这些冷气球对生物组织温度的影响仍然不清楚.
研究的目的:
- 为了评估和比较由AFA-Pro和POLARx冷热气球引起的组织温度变化.
- 在相关模型中研究不同冷却气球系统对生物组织的热效应.
主要方法:
- 使用猪心肌组织模型模拟肺静脉解剖和流动.
- 使用AFA-Pro和POLARx系统进行了受控的冷化.
- 在确认肺静脉封闭后,使用传感器测量了组织和气球温度.
主要成果:
- 与AFA-Pro (-41.5°C ± 4.9°C) 相比,POLARx (-58.4°C ± 5.9°C) 的平均组织点温度显著降低 (p<0.001).与AFA-Pro (-41.5°C ± 4.9°C) 相比,POLARx (-58.4°C ± 5.9°C) 的平均组织点温度显著降低 (p<0.001).
- 气球中位点温度的平均值也显著低于POLARx (-64.7°C ± 3.8°C) 与AFA-Pro (-54.6°C ± 2.6°C) 相比 (p<0.001).
- 这些发现表明POLARx系统的结能力更强.
结论:
- 与AFA-Pro.Pro相比,POLARx冷气球系统在生物组织上表现出明显更强的冷效应.
- 这种增强的结潜力可能有助于观察到的并发症率差异,特别是神经麻.
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