败血症幸存者的心脏功能障碍:一个范围审查
Kevin Garrity1,2, Samantha Gaw2, Alice Blewitt3
1University of Glasgow, Glasgow, UK kevin.garrity@glasgow.ac.uk.
Open heart
|December 8, 2023
概括
败血症幸存者面临心血管风险增加,但慢性心脏功能障碍仍然存在.
科学领域:
- 心脏病学 心脏病学
- 关键护理医学 关键护理医学
- 公共卫生 公共卫生
背景情况:
- 败血症显著增加心血管不良事件的风险,与已确定的风险因素相比.
- 败血症是重症监护室入院的主要原因,幸存者经常经历长期功能缺陷.
- 慢性心血管功能障碍在治疗败血症后功能障碍中的作用尚不清楚,需要对查和管理策略进行研究.
研究的目的:
- 进行范围审查,绘制出有关败血症后心血管功能障碍的现有证据.
- 确定有关毒症后心血管后果的机制,查和管理的研究缺口.
主要方法:
- 在MEDLINE,Embase和CINAHL数据库中进行了系统的文献搜索.
- 包括专注于成人心血管结果或败血症后症状的研究.
- 数据根据人口,心血管结果,客观措施 (生物标志物,成像) 和功能结果进行分类.
主要成果:
- 包括28项研究,报告了各种心血管结果,如心力衰竭,心律失常和心肌梗塞.
- 很大一部分研究 (61%) 没有包括对心血管功能的客观测量.
- 只有一个研究将客观心血管功能与患者报告的功能结果联系起来.
结论:
- 有关败血症后心脏功能障碍存在实质性的知识差距.
- 虽然败血症与不良心血管结果密切相关,但需要前性研究来阐明机制.
- 进一步的调查对于制定有效的策略来识别和管理处于危险的患者至关重要.
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