儿童重症监护室相关的睡眠和循环节调节障碍:一个专注的审查
Amanda B Hassinger1, Syeda Afzal2, Maya Rauth3
1Department of Pediatrics, University at Buffalo Jacobs School of Medicine and Biomedical Sciences; Division of Pulmonary and Sleep Medicine, John R. Oishei Children's Hospital of Buffalo, Buffalo, NY.
Seminars in pediatric neurology
|December 8, 2023
概括
在儿科重症监护室 (PICU) 中的重症儿童经历了睡眠模式的破坏和黑激素水平的改变. 需要使用标准化方法进行进一步的研究,以改善儿科睡眠和护理.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 睡眠科学 睡眠科学
- 循环生物学的日间运行时间.
背景情况:
- 儿科重症监护室 (PICU) 为儿童提供了破坏性的环境.
- 改善成人ICU睡眠与更好的结果相关;儿童的睡眠需求对生长和愈合至关重要.
- 有限的研究存在于儿科重症监护室的睡眠和昼夜节律.
研究的目的:
- 审查当前关于重症儿童睡眠和黑激素水平的知识.
- 确定研究中的差距,并建议在ICU中进行儿科睡眠研究的未来方向.
主要方法:
- 从20世纪90年代开始发表的14项观察性试验中的16篇文章的系统综述.
- 分析了312名重症儿童的睡眠数据和144名儿童的黑激素数据.
- 睡眠评估方法包括床边观察,动图,脑电图和多重睡眠学,其中多重睡眠学是最可靠的.
主要成果:
- 危急病的儿童表现出白天睡眠模式,睡眠碎片化,睡眠架构受到干扰.
- 在这个人群中,可能会出现升高和延迟的黑激素峰值.
- 睡眠障碍风险较高的子组包括患有败血症,烧伤,创伤性脑损伤和心胸外科手术后的人.
结论:
- 目前文献稀少,依赖于小型,单中心研究,采用多种方法.
- 验证的测量和标准化的定义对于未来的研究至关重要.
- 这个领域需要协调的方法来开发干预试验,并改善儿科重症监护病房的护理.
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