系统性炎症反应综合征在接受过导管大动脉植入术的患者中
Finn Syryca1, Costanza Pellegrini1, Tobias Rheude1
1Department of Cardiology, German Heart Center Munich, Technical University of Munich, Munich, Germany.
概括
系统性炎症反应综合征 (SIRS) 在过导管大动脉植入 (TAVI) 后很常见,增加了ICU停留时间. 然而,SIRS不会影响TAVI患者的1年心力衰竭再住院或2年死亡率.
科学领域:
- 心脏病学 心脏病学
- 密集护理医学 密集护理医学
- 外科手术的结果
背景情况:
- 有限的数据存在于系统性炎症反应综合征 (SIRS) 通过导管大动脉植入后 (TAVI).
- 之前对SIRS后TAVI的研究涉及小患者队列.
- 这项研究调查了SIRS在大量TAVI患者群体中的发病率和中期影响.
研究的目的:
- 为了确定TAVI后SIRS的发病率.
- 评估SIRS对TAVI患者的中期临床影响.
- 评估SIRS与重新住院和死亡率等结果之间的关联.
主要方法:
- 分析了一组717名接受TAVI治疗严重大动脉狭窄症的患者.
- 通过在手术后48小时内满足的特定标准来定义SIRS.
- 临床终点包括1年的慢性心力衰竭 (CHF) 再住院和2年的全因死亡率,使用Kaplan-Meier估计进行分析.
主要成果:
- 在TAVI患者中,SIRS发生在56.3%的患者中.
- 在经过扩张后并经历了主要血管并发症的患者中,SIRS更为频繁.
- 患有SIRS的患者在ICU停留时间较长 (1.56与1.22天,p=0.001),但在1年的CHF再住院或2年的全因死亡率中没有显著差异.
结论:
- 系统性炎症反应综合征是TAVI后的常见并发症.
- 在TAVI之后的SIRS可能会导致长时间住院.
- 在TAVI患者中,SIRS似乎不会影响1年或2年死亡结果.
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