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Updated: Jul 24, 2026

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通过组合优化设计的针对C型肝炎病毒的候选疫苗的测试.

Iker Malaina1,2, Luis Martinez3,4,5, David Salcines-Cuevas6

  • 1Department of Mathematics, University of the Basque Country (UPV/EHU), 48080, Bilbao, Spain. iker.malaina@ehu.eus.

Scientific reports
|December 8, 2023
PubMed
概括

一种新的疫苗设计程序优化了对诸如C型肝炎 (HCV) 等高度变化的病毒的表位选择. 这种方法确保了对病毒变异的广泛覆盖,从而导致安全和免疫原性疫苗候选人.

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Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...