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经过氧化处理的碳纳米管线加速神经元外生长,并在外围神经缺陷中诱导轴突再生

Atsushi Kunisaki1, Akira Kodama2, Masakazu Ishikawa1

  • 1Department of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Scientific reports
|December 8, 2023
PubMed
概括

经氧化处理的碳纳米管 (CNTs) 在大鼠中显著增强了外围神经再生. 这种方法改善了神经功能,减少了炎症和异物反应,为神经修复提供了一个有希望的策略.

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Neurogenesis and Regeneration of Nervous Tissue01:15

Neurogenesis and Regeneration of Nervous Tissue

In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
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