相关实验视频
Updated: Jul 29, 2026

08:50
Prostaglandin Extraction and Analysis in Caenorhabditis elegans
Published on: June 25, 2013
19.6K
火星素:来自Marsdenia tenacissima的一种新的孕乙烯
Arpita Srivastava1, Shashi Bala1, Naveen K Khare1
1Department of Chemistry, University of Lucknow, Lucknow, India.
Natural product research
|December 9, 2023
概括
研究人员从Marsdenia tenacissima.植物中分离出了一种新的pregnane化合物,12β-O-乙-20(S) -O-N-甲基兰-sarcostin. 它的结构使用先进的光谱和质谱技术来确定.
科学领域:
- 自然产品化学 自然产品化学
- 植物化学 植物化学
- 有机化学 有机化学
背景情况:
- 马斯迪亚坚固 (Marsdenia tenacissima) 是一种属于阿斯克莱皮亚科 (Asclepiadaceae) 家族的植物物种.
- 植物是各种化学化合物的丰富来源,具有潜在的生物活动.
研究的目的:
- 从Marsdenia tenacissima中分离和描述新的化学成分.
- 为了阐明一个新发现的pregnane衍生物的结构.
主要方法:
- 使用色谱技术将化合物分离出来.
- 使用核磁共振 (NMR) 光谱 (1H,13C,HMBC,HSQC,COSY,TOCSY) 的结构阐明.
- 质谱仪 (ESI-MS) 用于分子重量测定和碎片分析.
主要成果:
- 一种名为12β-O-乙-20(S) -O-N-methylanthranilyl-sarcostin的新孕妇衍生物被成功分离出来.
- 通过全面的光谱分析确定了新孕妇的完整结构.
- 隔离的化合物是一种醇pregn-5-ene衍生物.
结论:
- 这项研究成功地识别和表征了来自Marsdenia tenacissima的新型孕妇化合物.
- 这些发现有助于了解阿斯克莱皮亚科家族的植物化学多样性.
- 详细的结构信息为进一步调查该化合物的特性提供了基础.
相关概念视频
In-vitro Mutagenesis
To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
Spermatogenesis
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Transgenic Plants
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
Hormones of the Adrenal Glands
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and corticosterone...
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and corticosterone...
Gonadal and Placental Hormones
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair growth — and...
Spermatogenesis
Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...

