现代老年人的霍奇金淋巴瘤治疗方法
Andrew M Evens1, Marshall McKenna1, Yun Kyoung Ryu Tiger1
1Division of Blood Disorders, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ.
Hematology. American Society of Hematology. Education Program
|December 9, 2023
概括
优化老年人的霍奇金淋巴瘤 (HL) 治疗涉及老年人评估和多学科护理. 适合的患者可以从治疗意图治疗中获益,包括人环素,而不适合的患者需要个性化计划.
科学领域:
- 老年瘤学 老年瘤学
- 血液学恶性瘤是什么
背景情况:
- 全球范围内,关于老年霍奇金淋巴瘤 (HL) 患者的数据不断增加.
- 确定了关键的预后因素:晚年,并发症,功能状态,种族和剂量强度.
- 需要标准化的老年病评估 (GA) 和多学科护理.
研究的目的:
- 审查当前的数据,并为老年HL患者的管理提供建议.
- 强调老年医疗评估在治疗决策中的作用.
- 概述适合和不适合老年HL患者的最佳治疗策略.
主要方法:
- 关于老年HL患者最近的全球数据的审查.
- 对影响生存的预后因素的分析.
- 评估当前和新兴的治疗方式,包括化疗,向药物和检查点抑制剂.
主要成果:
- 老年评估 (GA) 对于客观测量患者状况至关重要.
- 适合老年HL患者应该接受含有 antracycline 的治疗方案,以治愈的意图.
- 布伦图西马布维多丁和检查点抑制剂显示出有前途,特别是在新的组合和不适合患者.
结论:
- 对于老年HL患者来说,多学科的管理和老年医疗评估是必不可少的.
- 治疗应该是个性化的,平衡治疗意图与毒性监测.
- 需要继续进行研究,以完善GA在该群体的治疗决策中的使用.
相关概念视频
Cancer Vaccines
376
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
376
Tumor Immunotherapy
529
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
529
Bone Marrow Sampling and Transplants
333
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
333
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K
Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K
Pulmonary Tuberculosis V
180
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
180


