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对不同本土的肠道微生物多样性分析和对来自的益生菌的查
Animals : an open access journal from MDPI
|December 9, 2023
概括
在高海拔的西藏和低海拔品种之间,肠道微生物群的差异很大. 特定的益生菌,如乳杆菌敏捷MH1和乳杆菌虫ZJ1显示提高健康的潜力.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 肠道微生物群对于的健康,免疫力和产量至关重要.
- 禽类益生菌可以增强免疫功能和性能.
- 了解微生物群变异是优化健康和开发益生菌的关键.
研究的目的:
- 研究中国本土在不同地理环境和品种的肠道微生物群差异.
- 从便中分离和描述潜在的益生菌.
- 分析隔离益生菌的基因组和功能性质.
主要方法:
- 来自140只中国本土和10只罗马的便微生物群的16S rRNA测序.
- 隔离和选潜在的益生菌菌株.
- 益生菌的基因组分析和功能分析 (抗结肠炎,免疫调节).
主要成果:
- 在高海拔藏和低海拔品种 (Meihua, Xuhai) 之间发现了显著的肠道微生物群变异.
- 确定了独特的微生物群落, *Cupriavidus* (高海拔地区) 和 *Candidatus_Bacilloplasma* (低海拔地区).
- 商业罗马层显示较低的阿尔法多样性比本地; brojlers 和层主要主持 Firmicutes, Bacteroidota 和 Proteobacteria.
- 益生菌 *Lactobacillus agilis* MH1 和 *Lactobacillus salivarius* ZJ1 显示出有利的基因组特征,抗结肠炎作用和免疫调节功能.
结论:
- 地理位置和品种在很大程度上影响了肠微生物群的组成和多样性.
- 本地肠道微生物群表现出独特的特征,受高度和品种的影响.
- 隔离的益生菌 *L. agilis* MH1 和 *L. salivarius* ZJ1 有望改善的健康和生产力.
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