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Updated: Jul 9, 2025

In Vitro Tumor Cell Rechallenge For Predictive Evaluation of Chimeric Antigen Receptor T Cell Antitumor Function
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克隆新抗原:免疫疗法反应的新兴"基于机制"的生物标志物

John Nemunaitis1, Laura Stanbery1, David Willoughby2

  • 1Gradalis, Inc., Dallas, TX 75225, USA.

Cancers
|December 9, 2023
PubMed
概括

克隆突变导致癌症. 高克隆瘤突变负担 (TMB) 预测更好的生存率和对检查点抑制剂的反应,与亚克隆TMB不同. 新型免疫疗法针对这些克隆新抗原.

关键词:
警觉的警觉 警觉的警觉生物标志物生物标志物癌症 癌症 癌症 癌症 癌症克隆性的新抗原.免疫疗法 免疫疗法

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