在患有慢性阻塞性肺部疾病的人群中,有或没有认知行为干预治疗呼吸困难的肺部康复:随机对照试验
Marie T Williams1, Hayley Lewthwaite1,2,3, Catherine Paquet1,4,5,6
1Allied Health and Human Performance, Innovation, IMPlementation and Clinical Translation in Health (IIMPACT), University of South Australia, Adelaide, SA 5000, Australia.
Journal of clinical medicine
|December 9, 2023
概括
将认知行为疗法 (CBT) 添加到综合性肺部康复计划 (CPRP) 中并没有显著改善慢性阻塞性肺部疾病 (COPD) 患者的健康结果. 这项研究发现,除了标准的CPRP外,对呼吸困难或身体功能没有任何额外的益处.
科学领域:
- 肺部医学 肺部医学
- 心理学 心理学 心理学
- 临床试验 临床试验
背景情况:
- 对于慢性阻塞性肺病 (COPD) 的认知行为疗法 (CBT) 的大多数试验都侧重于焦虑和抑郁.
- 这项研究调查了CBT在综合性肺部康复计划 (CPRP) 中对呼吸困难的影响.
研究的目的:
- 为了确定CPRP与CBT增强的呼吸不良是否提供优越的健康结果,与CPRP与社会群体对照相比.
- 评估CPRP+CBT与CPRP+社会控制对COPD患者焦虑,抑郁,运动能力和生活质量的影响.
主要方法:
- 一项实用随机对照试验,涉及101名中度至重度COPD的参与者.
- 参与者被随机分配到CPRP + CBT或CPRP + 社会控制.
- 包括医院焦虑和抑郁量表 (HADs) 和6分钟步行距离 (6MWD) 在内的健康结果在基线和干预后1,6和12个月被测量.
主要成果:
- 在CPRP+CBT和CPRP+社会对照组之间,在1,6或12个月的初级结局 (HADs,6MWD) 中没有发现显著差异.
- 呼吸困难,生活质量和习惯性体力活动等二次结果也没有显示出群体之间的显著差异.
- 参与者的特征相似,平均年龄为70岁,53%是男性.
结论:
- 与标准CPRP相比,将CBT与CPRP结合并没有为COPD患者带来额外的健康益处.
- 这些发现表明,标准的CPRP足以改善COPD队列中的健康结果.
- 可能需要进一步的研究来确定可能受益于CBT增强的特定患者子组.
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