一项为期十年的单中心研究检查了患者在开始长期腹膜透析后的生存率
Jesús Venegas-Ramírez1, Karla Esmeralda Barrios-Mora2, Eder Fernando Ríos-Bracamontes2
1Departamento de Nefrología, Hospital General de Zona No. 1, Instituto Mexicano del Seguro Social, Av. Lapislázuli 250, Col. El Haya, Villa de Álvarez 28984, Mexico.
Journal of clinical medicine
|December 9, 2023
概括
在墨西哥,慢性腹透析 (PD) 患者患有末期病 (ESKD) 的生存结果尚不清楚. 老年和持续的门诊PD增加了死亡风险,突出了优化治疗策略的必要性.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 腹腔透析 (PD) 是对末期脏疾病 (ESKD) 的经济有效的家庭治疗方法,在发展中国家越来越多地使用.
- 墨西哥长期PD患者的生存结果,这是一个ESKD负担很高的国家,没有充分记录.
研究的目的:
- 评估墨西哥长期PD患者的生存经验.
- 在这个患者队列中确定生存的决定因素.
主要方法:
- 一个单一中心的队列研究包括370名患者,在2013年2月至2023年1月期间启动了长期PD.
- 使用Kaplan-Meier和Cox比例危险回归分析来评估生存率及其预测因素.
主要成果:
- 总体死亡率为每1000人/月的4.7.
- 在PD开始后的24至36个月间,生存率显著下降.
- 在PD开始时的年龄较大和使用连续的门诊PD (与自动PD相比) 与死亡风险增加有关.
结论:
- 这项研究提供了关于墨西哥PD患者存活率的关键见解.
- 优化PD治疗策略对于改善ESKD患者的长期预后至关重要.
- 需要进一步的研究来阐明影响这一群体生存的因素.
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