患有ST升高心肌梗塞的患者的肥胖和急性损伤
Vojko Kanic1, David Suran1, Gregor Kompara1
1Division of Internal Medicine, Department of Cardiology and Angiology, University Medical Center Maribor, Ljubljanska Ulica 5, 2000 Maribor, Slovenia.
Journal of clinical medicine
|December 9, 2023
概括
肥胖不会增加ST升高心肌梗塞 (STEMI) 患者急性损伤 (AKI) 的风险. 然而,肥胖可能会在发展AKI的STEMI患者中提供生存益处.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肥胖医学 肥胖医学
背景情况:
- 关于ST升高心肌梗塞 (STEMI) 患者肥胖和急性损伤 (AKI) 之间的关系的数据有限.
- 这项研究调查了肥胖和AKI之间的关联,以及患者的治疗结果.
研究的目的:
- 评估体质指数 (BMI) 与STEMI患者的AKI发病率之间的关联.
- 评估肥胖对AKI和STEMI患者死亡率的影响.
主要方法:
- 一项回顾性研究包括3979名接受皮肤冠状动脉干预 (PCI) 的STEMI患者.
- 根据BMI对患者进行分类,并在30天和长期随访后对AKI发病率和死亡率进行比较.
主要成果:
- 在所有BMI类别中,AKI发病率相似,BMI和AKI之间没有显著的关联.
- AKI与显著更高的30天和长期死亡率有关.
- 肥胖与STEMI患者的长期死亡风险较低有关,特别是那些患有AKI的患者.
结论:
- 在STEMI患者中,AKI发生率似乎独立于BMI.
- 肥胖表明,在患有AKI的STEMI患者中,对长期死亡率有保护作用.
相关概念视频
External Anatomy of the Kidney
1.1K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.1K
Exercise and Cardiovascular Response
825
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
825
Heart Failure Drugs: Diuretics
395
Heart failure and kidney perfusion are interconnected in a complex way. Reduced renal perfusion and venous congestion are two significant factors that contribute to renal dysfunction in heart failure. The kidneys, primarily responsible for fluid balance in the body, are adversely affected due to compromised cardiac output and increased venous pressure. In response to reduced renal perfusion, the kidneys activate neurohumoral mechanisms to restore balance. However, these mechanisms can be...
395
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
436
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
436
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
161
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
161


