内部评估 休息代谢率变化与中年成人心脏代谢风险因素有关
Juan M A Alcantara1,2,3, Francisco J Osuna-Prieto4,5, Manuel J Castillo6,7
1Department of Health Sciences, Institute for Innovation & Sustainable Food Chain Development, Public University of Navarre, 31006 Pamplona, Spain.
Journal of clinical medicine
|December 9, 2023
概括
通过氧气消耗和能量消耗来衡量休息代谢率的变化,在男性和女性中显示出类似的模式. 这种变化可能表明中年成人心脏代谢健康状况.
科学领域:
- 代谢生理学 代谢生理学
- 心血管健康 心血管健康
- 人类生理学 人类生理学
背景情况:
- 内部评估休息代谢率 (RMR) 的变化与心脏代谢健康有关.
- 以前的研究表明,RMR变异性与健康结果之间存在关联.
- 在RMR变异性和其与心脏代谢风险因素的关联中,性别特异性的差异需要进一步调查.
研究的目的:
- 为了比较男性和女性之间的内部评估RMR变异性.
- 检查中年成人中RMR变异性 (VO2,VCO2,RER,REE的CV) 和心脏代谢风险因素之间的关联.
- 确定RMR变异性是否可以作为心脏代谢健康的指标.
主要方法:
- 间接热量测量用于测量72名中年成年人的气体交换 (VO2,VCO2,RER) 和休息能量消耗 (REE).
- 测量包括人体测量,身体组成,心肺呼吸能力,心脏代谢风险因素和心律参数.
- 评估内部的变化被表达为变化系数 (CV).
主要成果:
- 男人和女人在所有测量参数 (p > 0.05) 中表现出类似的内部评估RMR变异性.
- 在男性中,RER CV与BMI和肥胖度正相关,而VO2,VCO2和REE CV与心脏代谢风险因素负相关.
- 在女性中,VCO2和REECV显示与脂肪和心脏代谢风险Z-score的负相关性.
结论:
- 在中年成年人中,男性和女性之间的RMR变异性是可比的.
- RMR变化与心脏代谢风险因素相关,观察到性别特异性模式.
- 内部评估RMR变异性可以作为心脏代谢健康的潜在指标.
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