在接受过导管大动脉置换的患者中,心脏-脏关系
Teruhiko Imamura1, Hayato Fujioka1, Ryuichi Ushijima1
1The Second Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.
Journal of clinical medicine
|December 9, 2023
概括
在跨导管大动脉置换 (TAVR) 前的高体积指数 (SVI) 表明系统性拥堵,并预测心脏死亡或心力衰竭再入院的风险更高.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 血管生物学 血管生物学
背景情况:
- 脏的大小随着血液动力学波动而波动,充当血液体积缓冲器.
- 已经注意到心力衰竭和脏大小之间的联系,脏大小作为预后因素.
- 在接受过导管大动脉置换 (TAVR) 的患者中大小的临床意义尚不清楚.
研究的目的:
- 为了研究在TAVR之前患者的脏体积的预后影响.
- 为了确定脏体积是否可以预测TAVR后的不良心脏事件.
主要方法:
- 在2015年至2022年期间接受TAVR治疗的343名患者的回顾性分析.
- 从TAVR前的腹部CT扫描中测量体积.
- 索引体积 (SVI) 与2年心脏死亡或心力衰竭再入院之间的关联的评估.
主要成果:
- 较高的SVI与血体积增加和系统性拥堵相关.
- SVI独立地与2年心脏病死亡或心力衰竭再入院的风险更高有关 (HR1.09,p=0.041).
- 截止值SVI为70.2毫升/平方米,确定患者具有显著更高的不良事件率 (10%对4%,p=0.033).
结论:
- 升高的基线SVI表明系统性拥堵,并预测TAVR后更糟糕的结果.
- 在TAVR群体中,SVI可以作为一个有价值的预后标志物.
- 需要进一步的研究来阐明心脏-脏关系和SVI在TAVR患者中的作用.
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