在儿童群体中的喉喉逆流评分
Ivan Abičić1,2, Marina Čović3, Milorad Zjalić4
1Department of Otorhinolaryngology and Maxillofacial Surgery, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, 31000 Osijek, Croatia.
Journal of clinical medicine
|December 9, 2023
概括
儿科喉回流 (LPR) 可能涉及桃体中的素. 虽然在统计学上没有显著意义,但在 palatine 桃体中含有素的儿童中观察到更高的反流得分,这表明存在潜在的联系.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 儿科医学 儿科医学
背景情况:
- 喉回流 (LPR) 越来越多地在儿童中被诊断出来.
- 目前的LPR诊断依赖于病史和工具,如反流发现得分 (RFS) 和反流症状指数 (RSI).
- 素在LPR和桃体缩中的作用正在调查中.
研究的目的:
- 探索LPR表现和儿科唾液和口腔桃体中素存在之间的相关性.
- 评估素与儿童喉和喉症状的相关性.
主要方法:
- 使用问卷 (RSI,RFS) 调查的儿科患者.
- 通过西部斑点检测到唾液素.
- 使用免疫组织化学 (IHC) 评估了口腔桃体素的存在.
主要成果:
- 在IHC阳性和IHC阴性组之间,RFS和RSI没有显著差异.
- 在IHC阳性组中,中位数的RSI和RFS值趋向于上升.
- 表明升高的反流评分和桃体素之间存在潜在的关联.
结论:
- 在口腔桃体中素的存在可能与儿童的LPR症状严重程度相关.
- 需要进一步的研究来澄清桃体素在儿科LPR中的临床意义.
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