坚持健康的饮食模式和质瘤:一个匹配的病例对照研究
Weichunbai Zhang1, Yongqi He1, Ce Wang1
1Department of Neuro-Oncology, Cancer Center, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Nutrients
|December 9, 2023
概括
坚持健康的饮食模式,如地中海和DASH饮食,可以显著降低质瘤的风险. 这项研究强调了植物性食品和鱼类在降低癌症风险方面的保护作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 关于整体饮食与质瘤风险之间的联系的研究有限.
- 饮食越来越被认为是质瘤发展和预后的潜在因素.
研究的目的:
- 调查中国人群中遵守五种健康饮食模式与质瘤风险之间的关联.
- 使用主要成分分析 (PCA) 探索与质瘤风险相关的数据驱动的饮食模式.
主要方法:
- 一项基于医院的病例控制研究,涉及1012名参与者.
- 使用先验方法来评估遵守地中海,DASH,MIND,古石器和行星健康饮食.
- 使用主要成分分析 (PCA) 进行数据驱动的饮食模式探索.
主要成果:
- 坚持地中海,DASH,MIND和旧石器时代饮食与减少质瘤风险 (ORs从0.09到0.29) 有显著的关联.
- PCA表明,较高的植物性食品和鱼类摄入量,以及较低的碳水化合物,脂肪和盐的摄入量与质瘤风险的降低有关.
- 在地中海饮食中观察到非线性剂量反应关系;在DASH,MIND和古石器时代饮食中观察到线性关系.
结论:
- 特定的健康饮食模式,包括地中海,DASH,MIND和古石器时代的饮食,可能会对质瘤起到保护作用.
- 饮食选择,强调植物性食品和鱼类,同时限制加工品,是减少质瘤风险的潜在可修改因素.
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