自闭症谱系障碍中的微生物群:系统性审查
Zuzanna Lewandowska-Pietruszka1, Magdalena Figlerowicz1, Katarzyna Mazur-Melewska1
1Department of Infectious Diseases and Child Neurology, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
International journal of molecular sciences
|December 9, 2023
概括
患有自闭症谱系障碍 (ASD) 的儿童表现出肠道细菌的差异,通过益生菌和微生物群转移疗法可以看到潜在的改善,为肠-大脑轴提供了新的途径.
科学领域:
- 神经科学是一个神经科学.
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 自闭症谱系障碍 (ASD) 是一种神经发育状况,其核心症状包括社交互动和沟通困难.
- 许多患有自闭症的儿童患有胃肠道 (GI) 疾病,这可能会显著影响他们的生活质量.
- 新兴研究表明,肠道微生物群失调与ASD核心症状和肠道疾病之间存在联系.
结论:
- 肠道微生物群在肠-大脑轴中发挥着重要作用,影响着ASD核心症状和相关的肠道疾病.
- 微生物群转移疗法 (MTT) 显示出持久益处的前景,而益生菌需要进一步研究以确定其有效性.
- 标准化,全面的研究对于克服研究异质性和方法变异至关重要,为ASD有效的肠道向治疗铺平了道路.
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