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通过激活mTORC1信号通路,FARSB促进了肝细胞癌的进展

Yaofeng Wang1, Gengqiao Wang1, Shaobo Hu1

  • 1Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

International journal of molecular sciences
|December 9, 2023
PubMed
概括

人类氨酸tRNA合成酶 (PheRS) 的组成部分FARSB通过激活mTORC1信号和抑制铁亡,促进肝细胞癌 (HCC) 的进展. 高FARSB表达与低HCC患者存活率相关,表明其作为生物标志物的潜力.

关键词:
在FARSB中,FARSB是FARSB.猛禽猛禽是一种猛禽.铁性化 (ferroptosis) 是一种肝细胞癌是肝细胞癌.在 mTORC1 的情况下,mTORC1 是

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