迷幻药物的自然使用与情绪刺激的感知之间的关系:与事件相关的潜在研究,比较非用户和经验丰富的经典迷幻药物的用户
Paweł Orłowski1, Justyna Hobot2, Anastasia Ruban3
1Laboratory of Brain Imaging, Nencki Institute of Experimental Biology of Polish Academy of Sciences, Poland.
Journal of psychopharmacology (Oxford, England)
|December 9, 2023
概括
广泛使用自然主义的迷幻药物可能会降低对负面情绪刺激的反应性. 这项研究发现,与非用户相比,经验丰富的用户对恐惧面部的早期神经反应发生了改变.
科学领域:
- 神经科学是一个神经科学.
- 心理药理学 心理药理学
- 认知科学 认知科学
背景情况:
- 以前的研究表明,受控的迷幻药物使用调节了情绪反应.
- 迷幻药在自然环境中对情绪处理的影响仍然不清楚.
研究的目的:
- 研究经验丰富的自然主义迷幻药使用者与非使用者的情绪感知神经标记.
- 在不同组之间比较脑电图 (EEG) 与事件相关的潜在 (ERP) 组件.
主要方法:
- 横截面研究比较了56名经验丰富的迷幻药使用者 (≥15次终身使用) 与55名非使用者.
- 记录了EEG信号,而参与者看到了中性和情绪化的面部表情 (愤怒,悲伤,快乐).
- 分析了N170,N200,P200和P300的ERP组件作为情绪反应的指标.
主要成果:
- 迷幻药使用者对恐惧的面孔的N200幅度明显低于非使用者.
- 对于可怕的面部处理,观察到N170和N200幅度的群体差异.
- 在与注意力和认知相关的后来的ERP组件 (P200,P300) 中没有发现显著差异.
结论:
- 自然主义的迷幻药物使用似乎与对负面情绪刺激的反应性降低有关.
- 观察到的效应发生在情绪信息处理的早期,自动阶段.
- 这项研究提高了对现实世界的心理效应的理解.
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